Live Computerized Videomicroscopy of Cerebral Microvessels in Brain Slices
نویسندگان
چکیده
منابع مشابه
Live computerized videomicroscopy of cerebral microvessels in brain slices.
A model system for studying cerebral microvasculature is presented in which submerged in vitro brain slices are examined by computerized videomicroscopy. Brain slices are superfused continuously with artificial cerebrospinal fluid, while blood vessels are monitored using a transmission light microscope with water immersion objectives. The responses to well-characterized vasoactive compounds ind...
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The cndothelial cells of cerebral microvessels constitute a major site o f the blood-brain barrier. This barrier has physical and 'enzymic' components which together maintain the metabolic environment of the central nervous system. Major peptidase activities in cerebral microvessels are thought to be due to angiotensin-converting cnzymc (ACE) [ I ] and aminopeptidase(s) [2]. Although these enzy...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 1993
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.1993.86